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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'cc50b80c7d43a144ae8288677622ad5efebd4afb2bd36c79aa4f7dcbcfcac802' 
  AND token = 'Yah3EinyGqCb+Iv3+84w4IAgr/kF1oxJmpo8mrEqLqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}