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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '295beb513f32f84ab7992e13b512a2d7a7a3bb72812ecced0eb25a0191f1c842' 
  AND token = 'OgHW0w5xil1pIT0tbYm23k/sIn2choPrTNttcOKPVBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}