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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b21fd2118093b82b6b948cf96bac4ddbc6cae6b577fc7118a35000277daa43e5' 
  AND token = '1ibmf3LxBNdkVkG0DjXZjkmaRBWRvi5eH8T1ni/cgyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}