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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a5f1e0ec105f293a34c605420a0e4f1b1777b916006d5249908c70bade4c50ca' 
  AND token = 'lI3FpIrpkuiBwBHA6eO+M1cbk8QAPM6YxTht+p4vuCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}