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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '8c69daaa5750ee602a93990ceda93dae6013be08ef9dc974741171b2c4105b0a' 
  AND token = 'tKXGibn68NVmiKpoP3uvSZtTkY9/cQxA9ptN+ZEI68c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}