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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '366a6def8f715136ba6acfa0f9b5f46f9526c67c7c3787bf09381f9970c23c72' 
  AND token = 'xwAWX/ciPnAtWeFhLYspCllfytmoQsOU/2642IeGzrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}