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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '52de79d747ede1f250fb0cfcbab55a725d6fb6d62a21619c9200683aa46622ec' 
  AND token = 'I+F1D7uDmjIuemYVXfkTw5Zd8Y0u1JXui+CUyqc0VV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}