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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '7f94ca474a3effff6a5702f260c567c096e0482fbbdc7a9a51c2dba581954853' 
  AND token = 'vwSx8tBuZAP0jooDLW4LRqFtMDjysD9H0h30nrpBecA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}