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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6b8a8a9340c81921d3d268dd2853bbfe041aab5554146d8ada8bfdbe513fad3f' 
  AND token = 'mDFRV11t9LQDTS3gs+9RbhNUMd6tTByYXQ0FiZ34TnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}