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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '3726d919b61da09fd10d10852008e79f13b7a5455513ffe67ae0cbba77caf3ca' 
  AND token = '2c+8zCZ2+LDNxDWjDKD6IO4pIQSkrfd9N+w7rcdw7YM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}