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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '541252681a8dedee6693509d869bb4ebd221f12ba881ffa052655600dd25edbf' 
  AND token = 'i3SayiIZ59ufZJV/D6dl901rfq3t0pp1x8YaaT1K8mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}