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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'd22b0cb948469425724a0e8fc1081a35eacbf3ce343b2c1488ceb6f2344b6a25' 
  AND token = '09SWjKDhCGi4BAqbU4o4KDH0VjuD7a1uBJHk5UisCAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}