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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '81641bf6714331e395b4b2f0a4bc19ca93e31d41fbe7de4cf27986df540c4e2b' 
  AND token = 'ovxbJr1v1Huhjs9iz0WWXs5kxo7TfsBMHq19I0qzrl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}