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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'dac11e10c4fd4f71add1f3d9181258e6592803a1cebddc574d74579fc225d44f' 
  AND token = '+XUTjX8V+cMjAZTUNH36pPxzviHX/OmdCAdMOXkxJFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}