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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '72eb9fa531a2795b53f5d40ef773a94c5de912bc1b8e0b4541c4c8a396f1f2f1' 
  AND token = 'jXNfxlEEOevH25KxilBTAXpffphikLidB4BjWXWgMdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}