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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1ebdd4d962e64e5439b369252069137b9384a5b3a819e6e37ea46caf915cb330' 
  AND token = 'C3XK2cOu1ehT+AqjD2S18u8gvxUMIYvyLUeyEyu4oB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}