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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6a24ec740b80e6311348bbaa2249aa05fbf263265676e75b8c344b840cf168b0' 
  AND token = 'yLrUG8rkuoGeKMabXPBJwBo7nwnC1XmXLUBo2Hj9iFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}