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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '22329899a339b9c47f7945f701877fea27ce8438be4ece133e88049e11f8af24' 
  AND token = 'spcQdM3t+faxDp5noBaI/pgX6RajFP+JeLcvZPXbSJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}