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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '99e088c8a7f20ea14250d9586e9efcae6e1360e4342c328ad2607ee5098cd2d6' 
  AND token = 'zUb4PY5OskzIWQEBgB0jF4ybhUKw39I8Qln0XtXRIWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}