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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4b0c78327bef5fca0ec227abc80408a9d26700a414cf51c4e070a9d6199cc80f' 
  AND token = 'CUt6JSDlIpsNpRCI3RVSkUWzNFmz1Y/rrE008zK8LJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}