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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '30403940545244aa4283a43cf46d53c35c3e61cc45043928b48eb1923aedeec0' 
  AND token = '0q0EbNvp+z9q6h1X8uMWrYjwVKaXBPFkovCxjgInh4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}