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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'f2e87a1f2ad21495529b79ac6401b32a799c10015223adac9071522a40ee04cf' 
  AND token = 'VmdMdiTc/Vl6Of3FFSZMcWLvHJamT05iUeOfGCgST1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}