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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '808a17689dbb0f533dea15913576d208c9b3f60c8b14888f85f2f22f15f7b8ac' 
  AND token = 'vc/3TvQkvi07rwxQOcmuxa1tGs4xIzEbai3Qn4pNfFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}