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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '458ffa333a2aa23b5382312f0140233afe2fe2fdc60e95ae39d8c11678fa5804' 
  AND token = 'jnSz7Q7ic2jF7GDa28vlyj1eRctjLdqU7yYXSmlOEaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}