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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'b6bb61644e384b697e176217fd64e2e78142db23d31e3801c942d555ebeec3c8' 
  AND token = 'urwZk+JU27EBnumZ3sfsBS2JhyYEiDMqCW6bdLkvF7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}