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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '224eda8283c82953311b72d00b2409019f1eff4197e2c3bb5ae8c2b6bd6943f0' 
  AND token = 'yeZw3Z5k64wL1M16LqWugV1Twz5RpuheIsvFMuUbhOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}