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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '6ceb0aed3e24e420ba0960996aa2634193ddbe83e473de911ece92fc88341280' 
  AND token = 'zAtAgnH4CLEW6FzVB4qTGOqJbexyB1xuYATwzW8nau0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}