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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '45ccb13eb03e3e2f12d7a22aa9b8791e573f88438dcd6a8d17f012d5d4686474' 
  AND token = 'JnmRyho/tsJicYKtV13QXfuTakRYqNqNdYqWUYiKn80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}