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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '1b2782b5f09ba3871d0ea779735b999e4f790eeede3c446355edcfaff01b16e4' 
  AND token = 'yvzE6/Fev98GrSbgclu9ePhqjU0UoxaOp3Gnkro7qCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}