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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4aac281bca4567cb1bede72e991aa7b6fa4c9c5944ea246225116ee0d2fe41a1' 
  AND token = 'TyWBBEAO0kiI/XjUluczuJQpu7lFSzYWTiVWif7w9bA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}