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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'cde222bd35b22d23f015b463ecc7c5cd14129548d005433a6bfb017ae101822d' 
  AND token = 'lDNU7uSifyp3BTlVRJD4kRXqvnuW30PXXo+AkMqhnTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}