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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'afcd6191a3b3df6a4b8ff92b030450b8633fc37efc67f0b8d37298fe35939204' 
  AND token = 'dkMfIbdFKMtTfYfVu5mG3kWCyyskGK69I2/L3IpIkKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}