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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '154090ef6690af47025573ae46dd1ed8893cd92290268c9e9c5bc1b30ee7da56' 
  AND token = 'AGOEiQY0gLL6fKnoi9zMfr32S9ioYtqKRCnFuQu40Tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}