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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ae783a12c10b3ce720dbfedfb45e893162678ee5af736d899d0d9caa3bac8b16' 
  AND token = 'YmvVjmovB1py8dykOCSYU4EEyxaTZ6x2aD4vDR4wRqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}