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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'da74510d24408ce4996b2a4d7421afc08f3b12be84231b1de5fa4130538c94cc' 
  AND token = '7QaIuIOvCLI7mtm99U383IUMW92i+4/KfsqmgmjI5Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}