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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'eab7fe85d8af199962f80a604022a9ce5666846468a55861e40c37deee8ac36e' 
  AND token = '1cmpjAF2H28Y+lsHGUTs5FGfsrAMvIZwxHiK8W/y82A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}