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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '2d3a58f9941e01667f48e23e25e9dc810b517f1cb38fff37a4601e1e6896d304' 
  AND token = 'ZXL56DoQenuEDHRXfCgy49lb0GXecmsIkwLDSWyBaTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}