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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '43921fdbab35e86746e199babd795b1b7a0d2587ce61e9ad91077021b15b00ec' 
  AND token = 'M8JGEgmN9jS17nVAVCja0l3pQdLjFOcHQFHHj3IbePw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}