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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5118e0caf7242a56bf77d834b5f37352b81ddba3bc53fa3bedec80023d84d430' 
  AND token = 'IxWwORwLfqZM3piR/EBPwlbMihS38pnb5c2y06CtYjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}