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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '756006e257a0316d868d28d2a348285752e5e744073597cb55c8b46753cb6780' 
  AND token = 'yy2SvjNFdtN1Dj8yk3xBcrhU56JQXKWtgqEHoBV6L2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}