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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '440f340f4c4da81954e26fd788f663c3990a2d2fde11c3b0e79eede8d96ae788' 
  AND token = 'g4jSvGP4I7SRI/F1QGCyltwHck5ZHOxrg6pFwyo4KI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}