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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '7c8eef06f18b1261da30624b8c214b82cefbbefa30d33abf9eb135749499e7dd' 
  AND token = 'wzFTpiQH5zOK1jRF2tqOsctb4cRygAZkM6oQ9OB0YMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}