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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '74dc8abc19a2f21a2d25d32bbf6acf8486903a30fb7c8e46cae0281df883492b' 
  AND token = 'r1zRNKE1g0vfNIEjRQkrEKxVOUOOr0qW49+gHms3swc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}