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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '9293d2af0af10c027e8c019c98c1b1e462e3cf330e9ea035dd37783b8cfb9a5f' 
  AND token = 'CUcU42nFVssGp+49ak3Xt+C93sZnicllvwKeuWPfWkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}