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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'a0ef4e4f476804b9f5ea59348156ec87ffdfd04aa839148fd18101c6fd681d80' 
  AND token = '2HgRd3w2wZUNl1NHR9TkNw1dndHWMVWTDJpF84DV2qo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}