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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '5af569c780d5adb6dd2333847b41cb0246695847794e245f7977994727f70fcf' 
  AND token = 'G4HTsa0m59MXwvOIHcX7k/UjGiGSyDqt8Po9o5FgDuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}