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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '4674f3c95cc05a43546ad13abe78175f80371c5f2ee19bf56623e05c9f861da6' 
  AND token = 'TuabgBHKnb22N2OFBdKQEiwzAlN2Xs8I4z9OfBTP4X8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}