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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'cca9140b065b37129b92bd35362a702bef369412574bef2915d3031b0ea87bdb' 
  AND token = 'c3D2PaTsDWnS0CkUxs3mUa0h8qu5lZSllHqUGm436XI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}