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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = '9bdcec95e3b32a0868c1a3798df56aa00133196df7efd01df2a113de0c782ea2' 
  AND token = 'oSIu7MEgbKLzO17Xs1vyVdMobEgsewjWzLtCyVfYwyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}