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SELECT 
  1 
FROM 
  cscart_june_setuplock_keys 
WHERE 
  key_id = 'ea3f07611c9c6686416a601d0dde04228428efa965d9cc4c552206fba8bba653' 
  AND token = 'mD7niWDd1ZE58FcqbBEGAckg6JBcIVZ05PzEc1ldCTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}